![The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation - ScienceDirect The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S221112471831725X-fx1.jpg)
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation - ScienceDirect
![BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages - ScienceDirect BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124718316917-fx1.jpg)
BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages - ScienceDirect
![A) Bcl-2 family member effector proteins (Bax and Bak) oligomerize and... | Download Scientific Diagram A) Bcl-2 family member effector proteins (Bax and Bak) oligomerize and... | Download Scientific Diagram](https://www.researchgate.net/publication/273785165/figure/fig1/AS:294808330489858@1447299191294/A-Bcl-2-family-member-effector-proteins-Bax-and-Bak-oligomerize-and-permeablize-the.png)
A) Bcl-2 family member effector proteins (Bax and Bak) oligomerize and... | Download Scientific Diagram
Senescence Marker Protein 30 Has a Cardio-Protective Role in Doxorubicin-Induced Cardiac Dysfunction | PLOS ONE
![A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy | Cell Death & Disease A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy | Cell Death & Disease](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fcddis.2010.18/MediaObjects/41419_2010_Article_BFcddis201018_Fig1_HTML.jpg)
A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy | Cell Death & Disease
![Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c | Cell Death & Differentiation Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c | Cell Death & Differentiation](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fsj.cdd.4400783/MediaObjects/41418_2000_Article_BF4400783_Fig1_HTML.jpg)
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c | Cell Death & Differentiation
![Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance | EMBO reports Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance | EMBO reports](https://www.embopress.org/cms/asset/d7da0a91-5a42-4470-9205-a44744e13b16/embr201745235-fig-0007-m.jpg)
Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance | EMBO reports
![IJMS | Free Full-Text | Bcl-2 Family of Proteins in the Control of Mitochondrial Calcium Signalling: An Old Chap with New Roles | HTML IJMS | Free Full-Text | Bcl-2 Family of Proteins in the Control of Mitochondrial Calcium Signalling: An Old Chap with New Roles | HTML](https://www.mdpi.com/ijms/ijms-22-03730/article_deploy/html/images/ijms-22-03730-g001.png)